To be confused, anxious, worried, and/or upset (about something).
I’ve been tied up in knots trying to come up with a good topic for my term paper, but I just can’t think of anything!
James is tied in knots over how to break up with Danielle, but I think he needs to bite the bullet and just do it.
Frequently Asked Questions (FAQs)
The idiom ‘be tied (up) in knots’ means “to deal with a difficult situation without being harmed or damaged”
Example usage of idiom ‘be tied (up) in knots’: Newspapers have weathered the storm of online information by providing news online themselves.